Biotin only, 40000 IU without B12: no clear benefit, pain in p, and not much filling. Eyesight became very blurry and did not improve. After adding back 1000 mcg B12, eyesight improved. B12 cyanocobalamin with 10000 IU biotin caused pain in p

Liposomal hyaluronic acid internally: 4000 mg swallowed in a pill made my skin plump and softened the lines from under the eyes to the cheek substantially. Skin felt a bit numb, possibly from hyaluronic acid and water in the skin. The outside bottom of the eye pulled tight, making the eyes look smaller.

Liposomal NMN liquid used with DMSO seems to work at 1000 mg, perhaps even better than tablets and capsules.

Liposomal glutathione seems to give my face a subtle youthful look. It increased flesh on the side of the skin, removed a line on my chin by plumping it, and seemed to reduce and firm my jowls. It may have increased hair growth, possibly due to increased B12.